Role of satellite cells in skeletal muscle plasticity: Beyond muscle regeneration
نویسندگان
چکیده
منابع مشابه
Satellite cells in human skeletal muscle plasticity
Skeletal muscle satellite cells are considered to play a crucial role in muscle fiber maintenance, repair and remodeling. Our knowledge of the role of satellite cells in muscle fiber adaptation has traditionally relied on in vitro cell and in vivo animal models. Over the past decade, a genuine effort has been made to translate these results to humans under physiological conditions. Findings fro...
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Repair and regeneration of skeletal muscle in the postnatal mammal has long been supposed to be primarily or entirely accomplished by the population of satellite cells that are sequestered between the plasma membane of the muscle fibre and its overlying basement membrane. However it has never been clear whether all satellite cells participate and whether only satellite cells participate in this...
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Salamander limb regeneration depends on local progenitors whose progeny are recruited to the new limb. We previously identified a Pax7(+) cell population in skeletal muscle whose progeny have the potential to contribute to the regenerating limb. However, the plasticity of individual Pax7(+) cells, as well as their recovery within the new limb, was unclear. Here, we show that Pax7(+) cells remai...
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Introduction: Satellite cells are known as the main regenerative cell type in skeletal muscles. Our study established a modified digestion and preplating method for the isolation of slow or weak adherent cells for the enrichment of satellite cells. Low-survival rate of these primary stem cells prompted us to address whether cell culture medium substitution might change cell viability status. M...
متن کاملPlasticity of Salamander Skeletal Muscle Cells
Regeneration is unevenly spread throughout the animal kingdom. Some of the invertebrates have a very high regenerative capacity but the capacity to replace lost or damaged tissues in mammals is limited. Among the vertebrates, the aquatic salamanders are the champions of regeneration, being able to regenerate body parts such as their limbs, tail, and jaw. Understanding the celland molecular mach...
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ژورنال
عنوان ژورنال: The Journal of Physical Fitness and Sports Medicine
سال: 2017
ISSN: 2186-8123,2186-8131
DOI: 10.7600/jpfsm.6.89